Is Clobetasol Propionate Safe for Dogs?

Can I use clobetasol propionate on my dogs?

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Veterinarians do not use clobetasol propionate to treat dogs. There are multiple dog-appropriate topical steroids available. Therefore, veterinarians don't usually prescribe clobetasol to dogs with irritated skin. Learn more about this medication and why it isn't the top option when it comes to treating skin conditions in dogs.


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What is clobetasol propionate?

Clobetasol propionate is a high-potency topical corticosteroid that is used to treat skin disorders. You can only get this formulation with a prescription, as it is not available over the counter. Concentrated synthetic corticosteroids like clobetasol may be used to treat certain skin conditions, such as psoriasis and eczema, in humans.


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Because of its high potency — it is one of the strongest topical corticosteroids available — clobetasol should be used sparingly in veterinary medicine. When prescribed for humans, its use is limited to no longer than two weeks, and careful attention is paid to ensure proper dosage and strength.


What is clobetasol propionate used for?

Clobetasol propionate is a corticosteroid that is applied to the skin. Topical corticosteroid products, such as lotions and creams, are absorbed through the skin, helping to relieve itching and pain when used correctly.


Also, corticosteroids are immunosuppressant medications, so they work by limiting the body's immune response. As a result, they may help with reducing inflammation and redness, calming the skin, and supporting its healing.

However, corticosteroids can suppress the adrenal glands and can cause signs of Cushing's disease in dogs and humans.


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Is clobetasol propionate safe for dogs?

Clobetasol propionate is not considered the best topical medication for dogs.‌ There are safer and less aggressive options that will likely be used to treat your pet's skin ailment.


For example, some dogs with environmental allergies who are diagnosed with atopy or atopic dermatitis might need medicated shampoos. Those shampoos might contain ingredients like hydrocortisone, chlorhexidine, or the anti-fungal drug miconazole. Your veterinarian will determine the right treatment based on your pet's condition and needs.



Even if an individual in your household is using clobetasol propionate cream on themself, it's imperative that none of it gets on any of your pets. Avoid touching or holding your pet if you've applied this medication to your skin and wash your hands thoroughly after handling it.


What are the side effects of clobetasol propionate in dogs?

Clobetasol propionate side effects might include:

  • Itching
  • Burning
  • Stinging
  • Allergic reactions

In the event that your veterinarian does prescribe this medication, talk to them about potential side effects before administering it. That way, you'll know what to look for. If your pet develops symptoms, let your veterinarian know right away.

A serious allergic reaction is a medical emergency. Alert your veterinarian immediately if your dog experiences severe symptoms, such as trouble breathing or facial swelling, after coming into contact with clobetasol propionate.

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What are some options for treating a dog’s skin disorders?

To treat skin problems in dogs, several corticosteroids are commonly prescribed. They include betamethasone, triamcinolone, and prednisone.

  • Betamethasone‌ is often dispensed in a spray form that also contains an antibiotic. Some dogs who have been diagnosed with chronic skin infections, such as from allergies, might benefit from this medication.
  • Triamcinolone‌ is often administered as a topical spray or an injection to help reduce skin problems like inflammation. It can also be prescribed as a tablet, and in that case, it may be used when treating conditions like Addison's disease.
  • Prednisone‌ is often prescribed in tablet form. It is used for various medical conditions that range from skin problems to cancer.


No matter which medication your veterinarian prescribes or which form it comes in, be sure to follow the dosage instructions carefully. Your veterinarian will tell you how to apply the medicine, how often it should be applied, and how long the treatment will last.

Also, when it comes to treating skin problems, you may need to put an Elizabethan collar on your dog to prevent them from biting, licking, or scratching the affected area while it is being medicated.

The bottom line

Clobetasol propionate is a strong corticosteroid that has to be used with caution even when it is prescribed to humans. If your dog has a skin condition that requires treatment, it isn't likely that your veterinarian will prescribe this medication because there are less aggressive yet effective options available. Your veterinarian will be able to discuss more appropriate medicines that come with the least amount of risk for your canine.