The Best Cat Calming Sprays and Diffusers for Anxious Cats and Multi-Pet Homes

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Do you have a nervous cat? Cat calming sprays can be an effective way to support cats to be less stressed. These calming sprays can help cats who are struggling to get along with other pets, or can be used proactively to support cats when their families are preparing to move. These calming sprays work by dispersing artificial pheromones that mimic a cat's natural pheromones to help relax cats. Incorporating calming sprays into your cat's life can help cats adjust to stressful changes in the home and can also reduce the frequency of some stress-related behavioral challenges


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What to consider before purchasing a calming spray or diffuser

Veterinary Support:​ If you are struggling with your cat's anxiety or behavior it's important to consult with your cat's veterinarian. Changes in behavior and temperament can be a sign of pain or illness. Your vet will be able to assess your cat's health and provide treatment for any underlying conditions.


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Directed Use​: For your cat's safety make sure to follow all instructions associated with any calming spray that you use with your cat. Check instructions for how frequently it can be applied, if it should be sprayed in the air, or applied to cat beds and other fabric. Keep spray bottles away from your cat and other pets.


Supervise:​ When introducing a calming spray into your cat's environment be sure to closely supervise your cat to determine their response. If your cat seems upset, bothered, or stressed by the introduction of calming spray, discontinue use immediately.

The best diffuser spray

Feliway 30 Day Multicat Diffuser Plug-in Starter Kit

$24.99 at Amazon


This calming cat spray helps to reduce conflict and challenges between multiple cats in the home. This spray can be used to make introductions between cats go easier. This calming spray comes with a plug-in diffuser which provides slow release of the spray in your home. The diffuser covers up to 700 square feet with calming pheromones to help cats relax. The calming spray is a drug-free solution which has been developed to mimic a cat's natural pheromones. It can reduce instances of fighting and chasing with cats in the house to encourage better relationships between cats.


The best anxiety spray

Vet Classics Safety Zone Calming Spray for Dogs, Cats with Anxiety

$15.99 at Amazon



This calming spray can help to alleviate cat anxiety during stressful situations. This herbal calming spray is infused with pheromones and a blend of botanicals and can be used during vet visits, fireworks, and other stressful situations. This calming spray includes chamomile extract, clove oil, and rosemary oil. To use, spray the calming spray into a cat's crate, or part of your home, or vehicle five minutes before bringing your cat into the area.


The best calming spray

ThunderEase Cat Calming Pheromone Spray | Powered by FELIWAY | Reduce Anxiety During Travel, Vet Visits and Boarding

$19.99 at Amazon


This portable cat calming spray is specifically developed to help reduce a cat's behavioral challenges. Use of this spray can help with reducing or eliminating urine spraying as well as scratching. This calming spray helps keep cats calm and relaxed, and reducing their anxiety can help minimize those behaviors. This spray can be used at home, when traveling, or bringing your cat to the vet. The pheromone spray mimics a mother cat's natural nursing pheromones. This calming spray can be sprayed directly onto carpet, furniture, or cat carriers to help increase calm feelings for cats.

The best behavior support calming spray

Comfort Zone Spray & Scratch Control Calming Spray for Cats

$14.99 at Chewy


This calming spray is odorless and can be sprayed on any area of your home, including furniture and doors where your cat has a history of trying to mark with urine or scratch. The spray can also be used on cat scratchers and beds. This calming spray is odorless and doesn't have an impact on other pets in the home. The use of a calming spray can support your cat's overall calm behaviors. Regular use of this spray can help to reduce stress amongst cats in the home. You can also use this calming spray in higher stress situations, such as when grooming your cat or taking your cat to the veterinarian. Using the spray in stressful situations can help cats develop more positive relationships to these previous stressors.

The best long-lasting calming spray

Nature's Miracle Just For Cats Calming Spray, 8-oz bottle

$10.49 at Chewy

This stress-reducing calming formula can support cats with adjusting to stressful situations. This calming spray is non-sedating and won't alter your cat's overall temperament. This calming spray includes soothing scents which can help cats to be less stressed during day-to-day experiences, as well as with travel and separation from their family. For maximum effect, use the calming spray in areas of the house or car where your cat will be spending time.

The best catnip calming spray

bSerene Pheromone & Catnip Oil Calming Spray for Cats, 2-oz

$34.99 at Chewy


For stressed out cats, this calming spray can help cats calm down and reduce the symptoms of anxiety. This calming spray combines pheromones as well as catnip oil to calm and support cats. This calming spray is drug-free and encourages feelings of safety. This calming spray releases calming signals into the cat's environment that mimic naturally produced pheromones to increase a cat's overall feeling of security. To use, you can spray this catnip and pheromone spray onto furniture and other objects around your home where your cat spends time sleeping, playing, and relaxing. This spray is developed to help improve a cat's overall behavior and increase scratching in desired locations.

The best overall calming spray for cats

Feliway Classic Calming Spray for Cats, 60 mL

$23.95 at Chewy

This calming spray is a drug-free option to help reduce symptoms of stress in cats. It can be used during any stressful situation including vet visits, moving, or travel. This formula can be sprayed directly onto any area of the house where your cat spends time, or areas where your cat has a history of urine marking. This calming spray mimics naturally produced pheromones to encourage calm, and comfortable behavior and feelings.

The best aromatherapy calming spray

Jackson Galaxy Solutions Bully Pet Aromatherapy for Dogs & Cats, 2-oz

$26.95 at Chewy


Bringing together calming herbs, this holistic calming spray encourages overall cat wellness and behavior. This calming formula can be sprayed into the air in your home, onto your cat's toys, or added directly into your cat's food and water. It is specifically developed to help reduce conflict amongst cats in the home. This cat calming spray can also encourage better relationships between multiple cats in the home. The spray is made with 21 flower essences to encourage calm behavior and reduce feline stress.

The best travel calming spray

Remedi Animal Solutions Cat-14 Travel Anxiety Relief Cat Supplement, 1-oz bottle

$29.99 at Chewy

This calming formula is free from drugs or antibiotics but nevertheless supports cats to be calm during transitions or stressful times. This calming spray can be sprayed into the home, rubbed into your cat's mouth, or included in the drinking water. It is made specifically to support travel-related stress. This calming spray is fast-acting and can naturally help cats to adjust to changes in their environment. Each bottle contains 100 doses of calming support for a cat.

The best multi-pet calming cat spray

Pet Remedy Natural Calming Spray for Dogs & Cats, 200-mL

$36.66 at Chewy

This calming spray is effective for both cats and dogs, making it ideal for multi-pet homes. The ingredients include essential oils like sage, sweet basil, and valerian. This spray encourages a cat's body to produce calming neurotransmitters to encourage calm behavior. You can use this spray in your car when traveling, or around your home in your cat's favorite nap spots to encourage good and calm feelings. This spray can also encourage calmer dynamics between pets in the home.